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Mononucleosis spreads by contact with moisture from the mouth and throat of a person who is infected with the virus. After three to five days, any combination of the more intense symptoms and signs of mono may become present, including: severe sore throat, fever, swollen glands in the neck, armpits and groin, nausea, vomiting, upset stomach, enlarged spleen, enlarged liver, swollen eyelids.
In addition to kissing; sharing drinking glasses, eating utensils, and toothbrushes, or touching anything that has been near the mouth of an infected person, may result in transmission of the disease.
Vigorous contact sports should be avoided in the illness and recovery phase to prevent rupture of the spleen.